Comparing Intraoperative High Flow Nasal Cannula Therapy and Convetional Oxygen Therapy in Preventing Perioperative Hypoxaemia In Elderly Patients Undergoing Orthopaedic Surgery: A Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Incident of intraoperative desaturation
研究概览
简要总结
To study the effect of high flow nasal cannula in comparisons with nasoprong used intraoperatively in patients oxygenation status
详细描述
To observe the effect of high flow nasal cannula used intraoperatively compared to normal oxygen therapy (nasoprong) at a same fraction of inspired oxygen (FiO2) in elderly patients who are going for orthopaedic surgeries under central neuraxial block.
oxygenation will be access with intermittent blood gas. atelectasis will be access via chest x-ray , compared to a baseline chest x-ray, validated by a blinded radiologist
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
盲法说明
there will be no masking except for the radiologist who compares the postoperative chest x-ray with the baseline
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists (ASA) I, II or III patients.
- •Patients age 60 years and above
- •Patients scheduled for total knee replacement therapy and hip surgeries under central neuraxial block under the elective and emergency list.
排除标准
- •Patients with pre-operative spO2<94%
- •Patients delirious or demented / unable to give consent.
- •Patients with pre-existing pneumonia (defined as the initiation of antibiotics for suspected infection with one or more of the following: new or changed sputum; new or changed lung opacities; fever; white blood cell count >12 × 109 litre-1 )15
结局指标
主要结局
Incident of intraoperative desaturation
时间窗: From induction time until end of surgery
desaturation is taken as any spO2 \<94%
Patient comfort on high flow nasal cannula
时间窗: At end of surgery till discharge to ward (recovery area)
Patient rate comfort level using Visual Numerical Scale. The scale of 1 to 5 with 1 being extreme discomfort, 3 neutral and 5 extreme comfort
Atelactasis
时间窗: From end of operation until 24 hours post surgery
Incident of postoperative atelectasis by compraring the preoperative and postoperative chest x ray by a radiologist
次要结局
- Length of hospital stay(Time of hospital admission to time of discharge up to 30 days which ever come first)