Comparison of effect of High Flow Nasal Cannula with Continuous Positive Airway Pressure in reducing incidence of invasive mechanical ventilation in severe COVID 19 patients.
Not Applicable
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhereHealth Condition 2: J96- Respiratory failure, not elsewhereclassified
- Registration Number
- CTRI/2021/04/032501
- Lead Sponsor
- SRM Medical College and Research Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All COVID -19 positive patients ( by RT-PCR) with paO2/Fio2 (P/F) ââ?¬â?? 150 to 250, with good sensorium, stable hemodynamics and pH > 7.2
Absence of nasal pathology
Exclusion Criteria
Hemodynamically unstable patients
Patients in shock/ severe acidosis
Epistaxis, basal skull fracture
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of High Flow Nasal Cannula and Non Invasive Ventilation -Continuous Positive Airway Pressure in reducing need for invasive mechanical ventilation in patients with ARDS in COVID-19.Timepoint: 24 hours
- Secondary Outcome Measures
Name Time Method Ability of ROX index to identify COVID 19 patients on HFNC requiring invasive mechanical ventilation.Timepoint: 24 hours;Ability to alleviate dyspnoea as assessed by modified Borg scaleTimepoint: 24 hours;Patient�s compliance to therapy - comfort / noise level, ability to proneTimepoint: 24 hours