Neurodevelopmental Therapy for Spastic Cerebral Palsy

Not Applicable

Completed

• Conditions: Diplegia, Spastic; Cerebral Palsy; Spastic
• Interventions: Other: Neurodevelopmental therapy; Other: Routine physical therapy

• Registration Number: NCT05231538
• Lead Sponsor: University of Lahore

Brief Summary

This study was conducted to find out the Effects of Neurodevelopment therapy (a rehabilitative program designed by Bobath) on Gross Motor Function and Postural Control in Children with Spastic Cerebral Palsy. To investigate either there was a significant difference between the effects of neurodevelopment therapy and routine physical therapy on gross motor function and postural control in children with Spastic Cerebral Palsy.

Detailed Description

A randomized controlled trial was conducted at Department of pediatric rehabilitation, Sher e Rabbani Hospital, Sheikhupura. Sample size was 66 and purposive sampling technique was adopted to collect data. Sample selection was completely based on inclusion and exclusion criteria. A diagnosed Spastic Cerebral Palsy patient aged 2-6 years with no other severe abnormalities such as seizure were recruited. While patients with mental retardation or undergone medical procedures likely to affect motor function such as botulinum toxin injections, orthopedic remedial surgery were excluded. Data was collected at baseline, 4th, 8th and 12th week of the treatment sessions. Gross motor function measure scale (GMFM-88) and posture and postural ability scale (PPAS) were used as data collection tools.

Study Timeline

• Study Start: 2021-06-17
• Primary Completion: 2021-12-15
• Study Completion: 2021-12-31
• Status Verified: 2022-01
• Study First Submitted: 2022-01-15
• Study First Submitted QC: 2022-01-29
• Last Update Submitted: 2022-01-29
• Study First Posted: 2022-02-09
• Last Update Posted: 2022-02-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

• • A diagnosed Spastic Cerebral Palsy (patient's diagnosis of CP confirmed by an expert pediatrician neurologist)

  • Spastic CP
  • No other severe abnormalities such as seizure
  • Aged 2-6 years
  • Both Genders

Exclusion Criteria

• Medical procedures likely to affect motor function such as botulinum toxin injections
• Orthopedic remedial surgery
• Mental retardation, or a learning disability.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Neurodevelopmental Therapy	Neurodevelopmental therapy	The treatment group received neurodevelopment treatment lasting for 3 months (3sessions per week). Additionally, for this study, the NDT programme included passive stretching of the lower limb muscles (e.g. hamstrings, gastrocsoleus), followed by techniques of reducing spasticity and facilitating more normal patterns of movement while working on motor functions. In each session, exercises included patients sustaining themselves on their forearms and hands, sitting, crawling, semi-kneeling, and in standing positions supported by the Physical therapist until tone reduction achieved. Balance and corrective reactions were developed by using a CP ball and tilt board.
Routine Physical Therapy	Routine physical therapy	The control group underwent the exercises (stretching, passive range of motion, and active range of motion).

Primary Outcome Measures

Name	Time	Method
The Posture and Postural Ability Scale (PPAS)	12 weeks	The Posture and Postural Ability Scale (PPAS) is a 7-point ordinal scale for the assessment of postural ability in standing, sitting, supine and prone. There are six items for assessment of quality of posture in the frontal plane and another six items in the sagittal plane
Gross Motor Function Scale (GMFS)	12 weeks	The Gross motor function scale (GMFS) is a standardized observational instrument designed and validated to measure change in gross motor function over time in children with cerebral palsy. The scoring system of the GMFM is a four-point scale divided into five categories lying and rolling; sitting; crawling and kneeling; standing; walking, running

Trial Locations

Locations (1)

The University of Lahore Teaching Hospital; 🇵🇰 Lahore, Punjab, Pakistan