Mild ovarian stimulation in women with poor ovarian response undergoing IVF and ICSI.

• Conditions: Poor ovarian response; mild ovarian stimulation; IVF; ICSI

• Registration Number: NL-OMON26313
• Lead Sponsor: on

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 400

Inclusion Criteria

1. Valid indication for IVF or ICSI;

2. Patients with expected or non expected poor response:

Exclusion Criteria

1. Women > 43 years old;

2. Polycystic ovary syndrome or any other anovulation;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ongoing pregnancy (OPR) per women randomised (defined as a viable pregnancy of at least 10 weeks of gestation).

Secondary Outcome Measures

Name	Time	Method
1. Clinical pregnancy, defined as any registered embryonic heartbeat at sonography;<br /><br>2. Biochemical pregnancy ((defined as an increase in serum HCG or a positive pregnancy test);<br /><br>3. Multiple pregnancy, defined as registered heartbeat of at least two foetuses at 6-8 weeks of gestation;<br /><br>4. Miscarriage rate;<br /><br>5. Fertilization rate;<br /><br>6. Number of oocytes;<br /><br>7. Number of metaphase II oocytes;<br /><br>8. Number of embryos;<br /><br>9. Number of ET;<br /><br>10. Number of embryos frozen;<br /><br>11. Total FSH dose used for ovarian stimulation;<br /><br>12. Cancellation rate;<br /><br>13. Drop-out rate;<br /><br>14. Costs.