Mild ovarian stimulation and poor ovarian response.
Recruiting
- Conditions
- Poor ovarian response, mild ovarian stimulation, IVF/ICSI
- Registration Number
- NL-OMON24900
- Lead Sponsor
- Academic Medical Center- University of Amsterdam- Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 394
Inclusion Criteria
The couple who has a poor fertility prospects are eligible if the following apply:
1. Valid indication for IVF or ICSI;
Exclusion Criteria
1. Women > 43 years old;
2. Polycystic ovary syndrome or any other anovulation;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ongoing pregnancy (OPR) per women randomised (defined as a viable pregnancy of at least 10 weeks of gestation).
- Secondary Outcome Measures
Name Time Method 1. Clinical pregnancy, defined as any registered embryonic heartbeat at sonography;<br /><br>2. Biochemical pregnancy ((defined as an increase in serum HCG or a positive pregnancy test);<br /><br>3. Multiple pregnancy, defined as registered heartbeat of at least two foetuses at 6-8 weeks of gestation;<br /><br>4. Miscarriage rate;<br /><br>5. Fertilization rate;<br /><br>6. Number of oocytes;<br /><br>7. Number of metaphase II oocytes;<br /><br>8. Number of embryos;<br /><br>9. Number of ET;<br /><br>10. Number of embryos frozen;<br /><br>11. Total FSH dose used for ovarian stimulation;<br /><br>12. Cancellation rate;<br /><br>13. Drop-out rate;<br /><br>14. Costs;<br /><br>15. Patient discomfort/distress during IVF treatment.