nravelling the invisible infiltrating component of glioblastoma using MRI and a strong iron-like bloodpool contrast medium?
Recruiting
- Conditions
- Brain cancer10029211
- Registration Number
- NL-OMON53350
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
• Aged between 18 and 75 years
• Diagnosed with suspected glioblastoma
• Eligible for neurosurgical resection and/or chemoradiation therapy.
Exclusion Criteria
• Younger than 18 years old
• Patients unfit for surgery or lesions unsuitable for neurosurgical treatment
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Is it feasible to perform a study of USPIO neuro-imaging in healthy<br /><br>participants (n=6)?</p><br>
- Secondary Outcome Measures
Name Time Method <p>Can we robustly perform MR imaging of glioblastoma by use of a new Off Road<br /><br>multi-sequence protocol (i.e., T1w, T2w, FLAIR, DWI/DTI, SWI, T1w- and T2*w<br /><br>post-USPIO images) in 15 GBM patients to visualize tumor infiltration?<br /><br><br /><br>What is the diagostic accuracy of the Off Road imaging protocol to predict<br /><br>tumor recurrence?</p><br>