Out of Touch - How a temporary perturbation of the right temporoparietal junction (rTPJ) affects the brain network subserving body awareness.

Withdrawn

Conditions: Basic brain function in healthy humans
Body Awareness
Self-consciousness
10037176

Registration Number: NL-OMON48087

Lead Sponsor: Rijksuniversiteit Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Withdrawn

Sex: Not specified

Target Recruitment: 52

Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all of the following criteria:
1) Participants must be 18 years or older
2) Participants must be female
3) Participants must be right-handed
4) Participants must be capable of giving consent
5) Participants must be able to communicate in English

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:;1) A current diagnosis of a neurological disorder, i.e. epilepsy
2) A current diagnosis of psychiatric disorder
3) Presence of metallic devices, e.g. metal implants, non-removable piercings, or cardiac pacemaker
4) Psychotropic medication intake in the last 6 months
5) Claustrophobia
6) Alcohol or drug abuse
7) Refusal that general practitioner will be informed in the case of incidental findings of structural brain abnormalities
8) Use of medication related with increased epileptic seizure risk
9) Current tinnitus
10) (At risk of being) pregnant

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>For the first objective, changes in brain activation and functional<br /><br>connectivity will be measured before and after a single session of reptitive<br /><br>trancranial magnetic stimulation (rTMS) on the right temporo-parietal junction<br /><br>(rTPJ).<br /><br>The main study parameter will be changes resting-state fMRI measured in the<br /><br>BOLD (blood-oxygen-level-dependent) signal prior to and after repetitive TMS. </p><br>

Secondary Outcome Measures