Hemodynamic response assessed by the *HandScan* in hand and wrist joints of patients with osteoarthritis compared to patients with rheumatoid arthritis

Completed

• Conditions: 'OA'; 'RA'; 10003816; 10023213; Rheumatoid Arthritis; Osteoarthritis

• Registration Number: NL-OMON44590
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

* Diagnosed with Rheumatoid Arthritis according to ACR/EULAR 2010 criteria or with OsteoArthritis according to ACR 1990 criteria.
* Age between 18 and 90 years
* * 1 swollen hand joints
* Ability to give informed consent

Exclusion Criteria

* Other diagnosis than OA or RA that can explain pain or swelling in the hand joints, such as other inflammatory rheumatic diseases (psoriatic arthritis, gout).
* Intra-articular treatment with steroid injection within 3 months of assessments of the joints
* Trauma or surgery of one of the hand joints within 6 months of assessments of the joints
* Light sensitivity, i.e. Erythropoietic protoporphyria or patients on photodynamic therapy
* Artificial joints of wrist/hand

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>* Hemodynamic response, as provided standard by the HandScan (continuous value,<br /><br>0-3 per joint).<br /><br>* Inflammation defined by US: Gray scale (0-3 per joint) and Power Doppler (0-3<br /><br>per joint) </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Difference in disease characteristics detectable by US; bone osteophytes (0-1),<br /><br>tenosynovitis (0-1).</p><br>