Comparative study to modify harmful blood pressure and heart rate changes during placement of a tube inside windpipe for securing airway with dexmedetomidine and esmolol
Phase 1
- Conditions
- Health Condition 1: - Health Condition 2: I978- Other intraoperative and postprocedural complications and disorders of the circulatory system, not elsewhere classified
- Registration Number
- CTRI/2019/05/019172
- Lead Sponsor
- Vigneshwaran C
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA 1 and ASA 2
Exclusion Criteria
patients with ischemic heart disease, hypertension, Diabetes mellitus, pregnant, anticipated difficult airway, duration of laryngoscopy more than 20 seconds
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the clinical effects of dexmedetomidine and esmolol <br/ ><br>SBP,DBP,MAP,Heart rate,SpO2 recording <br/ ><br> <br/ ><br>Timepoint: SBP,DBP,MAP,Heart rate,SpO2 recording <br/ ><br>At baseline <br/ ><br>At 60 sec after infusion of dexmedetomidine/ <br/ ><br>esmolol <br/ ><br>Immediately after induction <br/ ><br>At 1 min after intubation <br/ ><br>At 3 min after intubation <br/ ><br>At 5 min after intubation <br/ ><br>At 10 min after intubation <br/ ><br>
- Secondary Outcome Measures
Name Time Method Attenuation of hemodynamic responses during laryngoscopy and endotracheal intubation.Timepoint: SBP,DBP,MAP,Heart rate,SpO2 recording <br/ ><br>At baseline <br/ ><br>at 60 sec after infusion of dexmedetomidine/ <br/ ><br>esmolol <br/ ><br>Immediately after induction <br/ ><br>At 1 min after intubation <br/ ><br>At 3 min after intubation <br/ ><br>At 5 min after intubation <br/ ><br>At 10 min after intubation <br/ ><br>