The difference of extubation time after target-controlled infusion of propofol anesthesia in pediatric patients undergoing long-duration surgery among age groups
- Conditions
- Emergence time and extubate time after long-duration infusion of propofol in children.Emergence time, extubate time, tci, propofol, pediatric anesthesia
Recruitment & Eligibility
- Status
- nknown
- Sex
- All
- Target Recruitment
- 52
1.Children aged 1 to 15 years old, 2.Patients with ASA physical status 1 - 3, 3.Patients who schedule for elective surgery with mild to moderate pain for more than or equal to 120 minutes duration, 4.Patients who require general anesthesia with an endotracheal tube and muscle relaxant and expected to extubate after the anesthesia
1.Patients who weigh less than the 5th percentile or greater than the 95th percentile
2.Patients with severe cardiovascular, neurological, hepatic, or renal impairment
3.Patient with a known allergy to any of the drugs involved in the study such as propofol (and its composition; soybean oil, egg, etc.), midazolam, fentanyl, cis-atracurium, lidocaine and ondansetron
4.Children with lower or upper respiratory tract infection having purulent nasal discharge, fever, or a cough
5.Patients with abnormal lipid or carbohydrate metabolism
6.Patients who being on anticonvulsants or psychiatric medications
7.Patients who require supplemental regional anesthesia or peripheral nerve block for pain control
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Extubation time immediately after finish operation time (min)
- Secondary Outcome Measures
Name Time Method Hemodynamic profile intraoperative Blood pressure,Percentage of time in targeted BIS intraoperative BIS,Sedation score after emergence in PACU Pediatric Sedation-Agitation Scale (P-SAS) ,Time to ready to discharge in PACU The Modified Aldrete Score,Propofol consumption intraoperative mg,Ce awake intraoperative from TCI device,Ce intubation intraoperative from TCI device