Evaluation the effects of L Carnitine on quality of life of the cirrhotic patients

Phase 3

Recruiting

• Conditions: iver cirrhosis.; Cirrhosis of the liver; K70, K74

• Registration Number: IRCT20180313039075N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Cirrhotic patients who referred to Liver clinic of Taleghani hospital withage 18-70 years old
Cirrhotic patients who referred to Liver clinic of Taleghani hospital with known case of cirrhosis
Cirrhotic patients who referred to Liver clinic of Taleghani hospital with Child score A or B
Cirrhotic patients who referred to Liver clinic of Taleghani hospital with no administration of L-Carnitine before

Exclusion Criteria

Not tolerate use of L-Carnitine because of the gastrointestinal problem
Gastrointestinal bleeding
Uncontrolled malignant tumors
Need of hemodialysis
Pregnancy
Receiving drugs causing hyperammonemia
Overt hepatic encephalopathy
Patients who do not accept to continue the study
Patients with other significant background diseases (heart failure, chronic kidney disease,…)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of life. Timepoint: First, 3 months later, 6 months later. Method of measurement: Standard questionnaire for quality life in cirrhotic patients.;Sarcopenia. Timepoint: First, 3 months later, 6 months later. Method of measurement: Evaluate gripe strength by dynamometer and muscle mass by bioelectrical impedance analysis (BIA).