NCT04855955No Longer Available不适用
Individual Patient Expanded Access Investigation New Drug (IND) Application for Administration of Autologous Human Adipose-Derived Mesenchymal Stem Cells in Alzheimer's Disease
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- No Longer Available
研究概览
简要总结
This is a single patient emergency expanded access clinical study to assess the safety of administering autologous AdMSCs to an incurable Alzheimer disease patient. The study subject will be evaluated for disease-associated severity according to symptoms, cognitive function, memory, and quality of life.
研究设计
- 研究类型
- Expanded Access
入排标准
- 接受健康志愿者
- 否
入选标准
- •The patient is diagnosed with later stage of Alzheimer Disease with sever cognitive disability.
- •All current anti-Alzheimer medicines cannot prevent disease progression and the patient's mental and physical ability persistently declined
- •Patient's legal guardian and caregiver must voluntarily sign an approved written consent form after ample explanation of the proposed therapy.
排除标准
- •Current diagnosis of malignancy
- •Renal/liver dysfunction: Exceed two times as normal subject
- •Pregnant or nursing
- •Received other trial drugs within 30 days after participation of this study
- •Experienced major surgery or trauma in the last 14 days
研究者
相似试验
Unknown
不适用
An Expanded Access IND for the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)Chronic Inflammatory Demyelinating PolyneuropathyNCT04825626Hope Biosciences Research Foundation
Unknown
不适用
Individual Patient Expanded Access IND of Autologous HB-adMSCs for the Treatment of Systemic Lupus Erythematosus (SLE)Lupus Erythematosus SystemNCT04907175Hope Biosciences Research Foundation
No Longer Available
不适用
Single Patient Protocol: A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in a Patient With Metastatic Cancer Plus the Administration of PembrolizumabNCT04135092National Institutes of Health Clinical Center (CC)
Unknown
不适用
Individual Patient Expanded Access IND of Hope Biosciences Autologous Adipose-derived Mesenchymal Stem Cells for Treatment of SCISpinal Cord Injury at C5-C7 LevelNCT03925649Hope Biosciences LLC
撤回
不适用
SINGLE PATIENT EXPANDED ACCESS OF A PROSPECTIVE, MULTICENTER CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND PROBABLE BENEFIT OF THE KERAKLEAR NON-PENETRATING KERATOPROSTHESIS IN SUBJECTS WITH CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANTCORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANTNCT03812341University of California, Irvine