Impact of Dehydration and Rapid Rehydration on Cognitive Function
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Dehydration
- Sponsor
- State University of New York at Buffalo
- Enrollment
- 15
- Locations
- 1
- Primary Endpoint
- Multitasking test
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The investigators want to understand the impact of the body losing and gaining water on brain function. Participants will restrict fluids consumed and exercise to lose 5% of body mass. Participants will then be provided fluid equal to the volume lost to consume over 2 hours (recovery). A series of brain function tests will be performed at baseline, following weight loss, and following recovery.
Detailed Description
A baseline series of brain function tests will be performed. Following this, participants will complete a 24 hour fluid and water rich food restriction on the day proceeding testing. Participants will then complete moderate to high intensity exercise in a hot/humid room to achieve 5% body mass loss. Once baseline core body temperature returns to baseline levels, the series of brain function tests will be performed. Participants will then consume a sports drink equal to the volume of sweat lost over the course of a 2 hour recover period. Following this, he series of brain function tests will be performed.
Investigators
Riana Pryor
Assistant Professor
State University of New York at Buffalo
Eligibility Criteria
Inclusion Criteria
- •Recreationally active
- •18-26 years old
Exclusion Criteria
- •History of cardiovascular, metabolic, respiratory, neural, or renal disease
- •Hypertensive (systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg) or tachycardic (resting heart rate ≥ 100 bpm) during the screening visit
- •Taking medication or supplements with a known side effect of affecting physiological responses to exercise (e.g., aspirin, acetaminophen, beta blockers, statins, stimulants, depressants, SSRIs)
- •Tobacco or nicotine use in the past six months
- •Current or past musculoskeletal injury impacting physical activity
- •Study physician discretion based on any other medical condition or medication
Outcomes
Primary Outcomes
Multitasking test
Time Frame: 2 hours following the dehydration cognitive function test, approximately 4.5 hours into the trial
Accuracy score of a multitasking test (0-100%) with greater scores indicating a better outcome