How do Small Changes in Hydration Influence Cognition: A Mechanistic Investigation
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Cognition
- 发起方
- Swansea University
- 入组人数
- 101
- 试验地点
- 1
- 主要终点
- Focused attention - Eriksen Flanker Task
- 状态
- 已完成
- 最后更新
- 6年前
概览
简要总结
The aim of this study is to determine whether drinking plain water when mildly dehydrated benefits cognitive performance and mood. Volunteers undergo a dehydration protocol designed to result in minor dehydration. While some participants receive two 150ml drinks of water others do not. Differences in cognitive functioning are assessed.
详细描述
As an essential nutrient, an inadequate intake of water has negative consequences: without a source of water death will occur in days. When Benton and Young (2015) reviewed the topic they concluded that in healthy adults, mild dehydration (in the range of a loss of 2% body mass) had been found to adversely influence mood and cognition. However, it is unclear at what degree of hypohydration these effects begin to emerge. This study was designed to determine whether small changes in hydration, of the level that might occur on a day to day basis, influence cognition and mood. During a dehydration protocol (sitting in a room heated to 30 degrees for four hours) young adult participants receive either drink two 150ml cups of water or nothing. Effects on memory, attention and mood are monitored.
研究者
入排标准
入选标准
- •In good general health i.e. no major health condition such as diabetes
- •BMI \< 30
排除标准
- •Not on blood pressure medication or blood thinning medication such as aspirin - No learning difficulty such as dyslexia
- •Gastro-intestinal disease
- •Cholesterol and BP
- •Dyslexic/dyspraxic
- •Depression or history of depression or other psychiatric disorder
结局指标
主要结局
Focused attention - Eriksen Flanker Task
时间窗: change from 0 to 180 minutes after the start of the dehydration protocol
The Arrow Flankers test measures the ability to direct attention and ignore peripheral information. Participants are required to indicate whether the middle arrow is pointing to the right or left by pressing the corresponding arrow on the keyboard. Either side of the central arrow are distractors. Both the average reaction times (in milliseconds) and accuracy are recorded. The difference in performance from baseline (before the intervention) is analysed.
Episodic memory - list of 30 words
时间窗: change from 0 to 180 minutes after the start of the dehydration protocol
Participants listen to a list of 30 words presented using a tape recorder. The words are of similar difficulty and matched for the number of syllables and frequency with which they occur in English. The subjects are asked to recall and write down as many words as possible. The difference in the total number of words remembered from baseline (before the intervention) is analysed.
次要结局
- Thirst (Participants rate their thirst)(change from 0 to 180 minutes after the start of the dehydration protocol)