how people with Parkinson’s disease can sense the position and movement of their legs (proprioception) and how this affects their ability to move and perform daily activities.

Not yet recruiting

Conditions: Parkinsons disease,

Registration Number: CTRI/2025/03/082837

Lead Sponsor: Sravani P N

Brief Summary: Parkinson’s is the second most common neurodegenerative disease. Parkinson’s disease is generally characterized by rigidity,tremor, bradykinesia, stooped posture, freezing of gait. Recent reports confirmthe presence of proprioception deficit in patients with Parkinson’sdisease. Increased neuronal responsesand noise within the basal ganglia lead to reduced joint specificity inproprioceptive integration, impairing accurate movement and coordination. This disruption impairs the brain’s capacity to accuratelyintegrate sensory signals, causing diminished awareness of limb and trunkpositions, particularly affecting kinesthesia (the sense of movement). As thedisease progresses, these proprioceptive disturbances worsen, contributing toincreasingly impaired movement coordination, greater challenges in motorcontrol . Mostof the studies are done proprioception in a single joint rather than using themulti-joint. where, Single-joint proprioception tests assess sensory feedbackfrom specific joints but may not capture the broader impact on overall limbfunction. Whole-limb assessments offer a more comprehensive evaluation byconsidering how proprioceptive deficits affect the coordination and executionof movements involving multiple joints and muscles. This approach provides abetter understanding of how proprioceptive impairments influence functionalactivities. Therefore, we could like to test single joint and multi-jointproprioception of lower limb in patients with Parkinson’s disease and to assessthe presence of variation and its impact on functional mobility like gaitpatients with Parkinson’s.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

Patient diagnosed with Parkinsons disease Adults with mild to moderate parkinsons disease If they able to walk independently with or without aid.

Exclusion Criteria

1.Individuals with cognitive impairment will be excluded from the study since they have difficulty understanding the instructions given.
2.Patients with early-onset PD and late stages of PD 3.A history of other neurological disease(s), or a history of severe ankle injury.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.JOINT REPOSITION TEST FOR HIP AND KNEE JOINT	One Time (1 day)
2.TARGET POINT	One Time (1 day)

Secondary Outcome Measures

Name	Time	Method
TIMED UP AND GO TEST

Trial Locations

Locations (1): Department of Neurology Sri Ramachandra Institute of Higher Education and Research
🇮🇳
Chennai, TAMIL NADU, India
Department of Neurology Sri Ramachandra Institute of Higher Education and Research
🇮🇳Chennai, TAMIL NADU, India
Radhika C M
Principal investigator
9841376961
radhikacm@sriramachandra.edu.in