跳至主要内容
临床试验/CTRI/2025/03/082837
CTRI/2025/03/082837尚未招募不适用

An Analysis Of Single And Multijoint Proprioception Of Lower Limb And Functional Mobility Among Patients With Parkinsons Disease

Sravani P N1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年3月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
1.JOINT REPOSITION TEST FOR HIP AND KNEE JOINT

研究概览

简要总结

Parkinson’s is the second most common neurodegenerative disease. Parkinson’s disease is generally characterized by rigidity,tremor, bradykinesia, stooped posture, freezing of gait. Recent reports confirmthe presence of proprioception deficit in patients with Parkinson’sdisease.  Increased neuronal responsesand noise within the basal ganglia lead to reduced joint specificity inproprioceptive integration, impairing accurate movement and coordination. This disruption impairs the brain’s capacity to accuratelyintegrate sensory signals, causing diminished awareness of limb and trunkpositions, particularly affecting kinesthesia (the sense of movement). As thedisease progresses, these proprioceptive disturbances worsen, contributing toincreasingly impaired movement coordination, greater challenges in motorcontrol . Mostof the studies are done proprioception in a single joint rather than using themulti-joint. where, Single-joint proprioception tests assess sensory feedbackfrom specific joints but may not capture the broader impact on overall limbfunction. Whole-limb assessments offer a more comprehensive evaluation byconsidering how proprioceptive deficits affect the coordination and executionof movements involving multiple joints and muscles. This approach provides abetter understanding of how proprioceptive impairments influence functionalactivities. Therefore, we could like to test single joint and multi-jointproprioception of lower limb in patients with Parkinson’s disease and to assessthe presence of variation and its impact on functional mobility like gaitpatients with Parkinson’s.

研究设计

研究类型
Observational

入排标准

年龄范围
40.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Patient diagnosed with Parkinsons disease Adults with mild to moderate parkinsons disease If they able to walk independently with or without aid.

排除标准

  • 1.Individuals with cognitive impairment will be excluded from the study since they have difficulty understanding the instructions given.
  • 2.Patients with early-onset PD and late stages of PD 3.A history of other neurological disease(s), or a history of severe ankle injury.

结局指标

主要结局

1.JOINT REPOSITION TEST FOR HIP AND KNEE JOINT

时间窗: One Time (1 day)

2.TARGET POINT

时间窗: One Time (1 day)

次要结局

  • TIMED UP AND GO TEST

研究者

发起方
Sravani P N
申办方类型
Other [self]

研究点 (1)

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