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A characteristic study on the curative effect of Bushen Zhuyun Recipe in the treatment of recurrent abortion by pre-pregnancy intervention and regulation of endometrial receptivity

Phase 2
Conditions
Habitual abortion
Registration Number
ITMCTR2022000031
Lead Sponsor
Xiyuan Hospital,
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Female
Target Recruitment
Not specified
Inclusion Criteria

(1) Meet the diagnostic criteria for recurrent miscarriage.
(2) Meet the diagnostic criteria for thin endometrium.
(3) Those who are in line with TCM syndrome differentiation as kidney and spleen deficiency syndrome.
(4) Aged 22-45 years old.
(5) The regularity of the menstrual cycle.
(6) Voluntarily sign the informed consent.

Exclusion Criteria

(1) Does not meet the inclusion criteria
(2) Three-dimensional B-ultrasound or hysteroscopy found intrauterine adhesions
(3) Taking other drugs that affect endometrial thickness.
(4) have uterine fibroids or reproductive tract malformations.
(5) Abnormal autoimmune antibodies, chromosomal abnormalities and other factors.
(6) Patients with other systemic heart, liver, kidney and other serious diseases.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Early pregnancy outcome;Endometrial thickness and type changes;
Secondary Outcome Measures
NameTimeMethod
Estradiol;Endometrial blood flow changes;pregnancy rate;Chinese medicine symptom complex score;progesterone;vascular endothelial growth factor;Interleukin-8;
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