Investigating the effect of royal jelly on blood cell count and fatigue in cancer patients undergoing chemotherapy.

Not Applicable

Recruiting

• Conditions: Condition 1: Stomach Cancer. Condition 2: Esophagus cancer. Condition 3: Malignant neoplasm of small intestine. Condition 4: Malignant neoplasm of colon. Condition 5: Malignant neoplasm of rectum. Condition 6: Malignant neoplasm of liver and intrahepatic bile ducts. Condition 7: Malignant neoplasm of bronchus and lung. Condition 8: Malignant neoplasm of heart, mediastinum and pleura. Condition 9: Breast cancer.; Malignant neoplasm of stomach; Malignant neoplasm of esophagus; Malignant neoplasm of small intestine; Malignant neoplasm of colon; Malignant neoplasm of rectum; Malignant neoplasm of liver and intrahepatic bile ducts; Malignant neoplasm of bronchus and lung; Malignant neoplasm of heart, mediastinum and pleura; Malignant neoplasm of breast

• Registration Number: IRCT20230328057779N1
• Lead Sponsor: Zanjan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 June 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

Cancer diagnosis recorded in the patient`s medical records
Receiving at least two courses of chemotherapy drugs.
Receiving drugs that suppress the bone marrow and cause pancytopenia with the approval and supervision of a respected oncology doctor.
Age above 18 years.
Consent to participate in the study.
Physical and hemodynamics stability.

Exclusion Criteria

Having a history of cardiovascular diseases, asthma and diabetes.
Having any major disabling medical and psychiatric conditions that would interfere with the evaluation.
Having a history of allergy to honey and honey products.
Age over 60 years

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood cell count includes the count of white blood cells, red blood cells, hemoglobin and platelets, which will be evaluated according to laboratory results. Timepoint: After the end of the second round of chemotherapy, the intervention is carried out using royal jelly and placebo for five days. After two weeks from the end of the intervention, direct evaluation will be done by the researcher. Method of measurement: Counting blood cells using laboratory results (CBC).

Secondary Outcome Measures

Name	Time	Method
Fatigue is evaluated using the Smet's Multidimensional Fatigue Assessment Questionnaire, which ranges from 20 to 100, and a higher score indicates more fatigue. Timepoint: After the end of the second round of chemotherapy, the intervention is carried out using royal jelly and placebo for five days. After two weeks from the end of the intervention, direct evaluation will be done by the researcher. Method of measurement: assessing fatigue using a 20-item questionnaire, Smet's multidimensional measurement of fatigue (Multidimensional Fatigue Inventory).