Effect of amlodipine on blood flow of preovulatory follicle in Polycystic ovarian patients: A Randomized Controlled Trial

Not Applicable

• Conditions: Fertility-female; infertility

• Registration Number: PACTR201309000638372
• Lead Sponsor: ational Research Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-09-05
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

a) Demographic features including
age of ¿20 & ¿35
BMI of ¿39
b) Infertility secondary to PCO, as indicated by amenorrhea or oligomenorrhea,
elevated serum LH levels,
normal or low FSH levels,
elevated LH/FSH ratio,
clinical evidence of androgen excess (acne, hirsutism, alopecia),
elevated serum levels of testosterone , ultrasound findings of enlarged ovaries with multiple small cysts (10-12 or more of 2-9 mm in diameter) scattered around the periphery and highly echogenic stroma.

Exclusion Criteria

other causes of infertility diagnosed during infertility work up, also,
hepatic,
cardiac, and
hypotensive patients

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
progesteron level;peak systolic velocity, Pulsatility indices and resistant indices of ovarian (vessel supplying preovulatory follicle) and uterine;size of dominant follicle or follicles

Secondary Outcome Measures

Name	Time	Method
endometrial thickness;pregnancy rate