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临床试验/CTRI/2025/03/082242
CTRI/2025/03/082242尚未招募不适用

Role Of Pre Emptive Ketamine In Post Operative Pain Control For Patients Undergoing Modified Radical Mastectomy

Dr Nadira1 个研究点 分布在 1 个国家目标入组 98 人开始时间: 2025年3月22日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
98
试验地点
1
主要终点
To assess the severity of post operative pain using Visual Analogue Scale score among post modified radical mastectomy patients who received and not received pre emptive ketamine.

研究概览

简要总结

This study is a prospective observational study to determine the role of pre emptive intravenous ketamine in post operative pain control of patients undergoing modified radical mastectomy.The primary objective of the study is to assess the severity of post operative pain using Visual Analogue Scale score among post modified radical mastectomy patients who received and not received pre emptive ketamine.And the secondary objective of the study is to asses the Interval time for first rescue analgesic,Total number and dose of analgesic injections in first 24 hours,Occurence of adverse effects like hallucination,delirium and visual disturbances within first 24 hours.This study helps in determining the role of intravenous ketamine as pre emptive analgesic and its post operative analgesic sparing effect on patients undergoing modified radical mastectomy.Low dose ketamine (less than 1mg/kg) helps in attaining adequate post operative pain with minimal adverse effects and haemodynamic changes.Adequate post operative analgesia with opioid sparing and minimal adverse effects can help in increasing patient satisfaction.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
Female

入选标准

  • Adult female patients aged between 18 to 80 years undergoing modified radical mastectomy.
  • American Society Of Anaesthesiologist (ASA) physical status I,II and III.

排除标准

  • Known history of drug or alcohol abuse Patients with chronic pain syndrome Past history of drug allergy Liver failure Renal insufficiency Cognitive impairment with difficulties in pain evaluation Psychiatric illness.

结局指标

主要结局

To assess the severity of post operative pain using Visual Analogue Scale score among post modified radical mastectomy patients who received and not received pre emptive ketamine.

时间窗: 30 minutes, 2 hours, 4 hours, 6 hours, 12 hours and 24 hours post operatively

次要结局

  • To assess the(Interval time for first rescue analgesic)

研究者

发起方
Dr Nadira
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Nadira

Government Medical College Kozhikode

研究点 (1)

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