Level of Serum Lactate Dehydrogenase in Immune Thrombocytopenia
Not yet recruiting
- Conditions
- Immune Thrombocytopenia (ITP)
- Registration Number
- NCT07046013
- Lead Sponsor
- Sohag University
- Brief Summary
Assessment of relation between serum lactate dehydrogenase and immune thrombocytopenia
- Detailed Description
Immune thrombocytopenia is an autoimmune disorder defined by a significantly reduced number of platelets in blood circulation.
Lactate dehydrogenase is a group of oxidoreductase isoenzymes catalyzing the reversible reaction between pyruvate and lactate.
The LDH was found to be moderately high in patients with immune thrombocytopenia at the time of diagnosis.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Thrombocytopenia patients at the time of diagnosis.
Exclusion Criteria
- bone fractures _ bone diseases_ malignancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relation between serum lactate dehydrogenase and immune thrombocytopenia About 2 years
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link elevated LDH levels to immune thrombocytopenia pathogenesis?
Are high serum LDH levels in ITP patients associated with specific autoimmune pathways or platelet destruction markers?
Can serum lactate dehydrogenase serve as a predictive biomarker for ITP treatment response to corticosteroids or IVIG?
What adverse events are commonly observed in ITP patients with elevated LDH levels and how are they managed?
How does serum lactate dehydrogenase correlate with disease severity or progression in adult-onset versus childhood-onset immune thrombocytopenia?