AV Node Isolation in Atrial Fibrillation vs. Modulation by "Pace and Ablate" Strategy
Completed
- Conditions
- AV Node AblationEscape; RhythmAtrial Fibrillation
- Interventions
- Procedure: AV-node isolationProcedure: AV-node ablation
- Registration Number
- NCT04859933
- Lead Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
- Brief Summary
AV-node ablation (AVNA) is a common therapy option for rate control strategy of permanent atrial fibrillation with numerous side effects. The investigators hypothesised that an isolation of the AV node is concomitant with less occurrence of new bundle brunch blocks, more frequent preservation and higher rate of escape rhythm compared to AVNA. This retrospective study includes 20 patients being treated with AV-node isolation (AVNI) and 40 historical AVNA-controls. Among others these two methods were compared regarding escape rhythm, delta QRS, procedure time, ablation points, fluoroscopy time and total dose area product (DAP).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- paroxysmal, persistend or permanent atrial fibrillation; indication for AVNA
Exclusion Criteria
- other indications for AVNA than atrial fibrillation as AVNRT, atrial flutter, atrial tachycardia
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description AVNI group AV-node isolation Inculudes all patients beeing treated with AV-node isolation AVNA group AV-node ablation Group of historical controls beeing treated with AV-node ablation
- Primary Outcome Measures
Name Time Method AV-node escape rhythm intraoperative, follow-up after 1 to 3 month bundle branch blocks intraoperative, follow-up after 1 to 3 month
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum
🇩🇪Bad Oeynhausen, Germany