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Clinical Trials/NCT04859933
NCT04859933
Completed
Not Applicable

AV Node Isolation in Atrial Fibrillation vs. Modulation by "Pace and Ablate" Strategy

Heart and Diabetes Center North-Rhine Westfalia1 site in 1 country60 target enrollmentStarted: October 1, 2020Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
Heart and Diabetes Center North-Rhine Westfalia
Enrollment
60
Locations
1
Primary Endpoint
AV-node escape rhythm

Overview

Brief Summary

AV-node ablation (AVNA) is a common therapy option for rate control strategy of permanent atrial fibrillation with numerous side effects. The investigators hypothesised that an isolation of the AV node is concomitant with less occurrence of new bundle brunch blocks, more frequent preservation and higher rate of escape rhythm compared to AVNA. This retrospective study includes 20 patients being treated with AV-node isolation (AVNI) and 40 historical AVNA-controls. Among others these two methods were compared regarding escape rhythm, delta QRS, procedure time, ablation points, fluoroscopy time and total dose area product (DAP).

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Retrospective

Eligibility Criteria

Ages
18 Years to 100 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • paroxysmal, persistend or permanent atrial fibrillation; indication for AVNA

Exclusion Criteria

  • other indications for AVNA than atrial fibrillation as AVNRT, atrial flutter, atrial tachycardia

Outcomes

Primary Outcomes

AV-node escape rhythm

Time Frame: intraoperative, follow-up after 1 to 3 month

bundle branch blocks

Time Frame: intraoperative, follow-up after 1 to 3 month

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Heart and Diabetes Center North-Rhine Westfalia
Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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