Node and Atrial Fibrillation Ablation for Persistent Atrial Fibrillation

Eastbourne General Hospital1 site in 1 country50 target enrollmentFebruary 2010

ConditionsPersistent Atrial Fibrillation

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Persistent Atrial Fibrillation
Sponsor: Eastbourne General Hospital
Enrollment: 50
Locations: 1
Primary Endpoint: To measure the two treatment effects on VO2 max over time by means of cardiopulmonary exercise testing.To measure the two treatment effects on 6-minute hall walk distance.Echocardiographic parameters
Last Updated: 15 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of the study is to assess combining AF ablation, with AV node ablation and pacemaker implantation for patients suffering with 'irregular heartbeats' or atrial fibrillation. The study will last 13 months.

Registry

clinicaltrials.gov

Start Date

February 2010

End Date

January 2012

Last Updated

15 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Eastbourne General Hospital

Eligibility Criteria

Inclusion Criteria

•Patients with symptomatic drug refractory atrial fibrillation.
•Patients who have had pacemaker implantation and AV node ablation with ongoing symptoms.
•Patients will already be refractory to at least 2 rate or rhythm control drugs.
•Patients must be over 18 years old.
•Patients give informed consent form prior to participating in this study.

Exclusion Criteria

•Patient is suffering with unstable angina in last 1 week.
•Patient has had a myocardial infarction within last 2 months.
•Patient is expecting or has had major cardiac surgery within last 2 months.
•Patient is participating in a conflicting study.
•Patient is unable to perform exercise testing.
•Patient is mentally incapacitated and cannot consent or comply with follow-up.
•Patient has NYHA class III/ IV heart failure.
•Patient has LVEF \<35% not secondary to tachycardia.
•Pregnancy.
•Patient suffers with other cardiac rhythm disorders.

Outcomes

Primary Outcomes

To measure the two treatment effects on VO2 max over time by means of cardiopulmonary exercise testing.To measure the two treatment effects on 6-minute hall walk distance.Echocardiographic parameters

Time Frame: 1 year