Clinical and Radiographic Evaluation of Autogenous Demineralized Dentin Graft for Ridge Preservation With and Without Injectable Platelet Rich Fibrin (A Randomized Controlled Clinical Trial)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Cairo University
- Enrollment
- 24
- Locations
- 1
- Primary Endpoint
- Radiographic Bucco-lingual ridge width change
Study Overview
Brief Summary
Ridge preservation should be considered whenever possible after tooth extraction. Whether implant placement would be performed or for aesthetic consideration at pontic sites when conventional bridge is planned. Ridge preservation aims to maximize the bone formation accompanied with good soft tissue architecture to facilitate implant and prosthetic replacement restoring function, phonetics and aesthetics. the Aim of the study is To evaluate the bucco-lingual ridge width clinically and radiographically, height of buccal and lingual ridges of the socket after application of injectable platelet rich fibrin and autogenous dentin graft.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Age ≥ 18 years need of at least one single rooted tooth extraction.
- •Non-restorable teeth.
- •Systemically healthy patients.
- •Good oral hygiene, Plaque index less than 15%.
- •Non-smoker or Smoking ≤ 10 cigarettes/day.
- •Cooperative patients able and accept to come for follow up appointments.
Exclusion Criteria
- •Any interim intervention that may have affected any of the outcomes of interest.
- •Pregnant and lactation females.
- •Smoking ˃ 10 cigarettes/day.
- •Patients reporting systemic conditions that may compromise healing or bone metabolism (eg: diabetes).
- •Patients with poor oral hygiene.
- •Any known allergies.
Arms & Interventions
injectable platelet rich fibrin with deminerlized dentin graft
injectable platelet rich fibrin with deminerlized dentin graft for ridge preservation after teeth extraction
Intervention: injectable platelet rich fibrin with demineralized dentin graft (Procedure)
deminerlized dentin graft
deminerlized dentin graft for ridge preservation after teeth extraction
Intervention: demineralized dentin graft (Procedure)
Outcomes
Primary Outcomes
Radiographic Bucco-lingual ridge width change
Time Frame: up to 24 weeks
radiographic measurement
Secondary Outcomes
- Changes in the height of the socket buccal and lingual ridges.(up to 24 weeks)
- postoperative pain(immediately after the procedure)
- Keratinized tissue width(up to 24 weeks)
- chair time(immediately after the procedure)
- Patient satisfaction(immediately after the procedure)
Investigators
Odai Amer Ahmad Hwafdeh
principal investigator
Cairo University