跳至主要内容
临床试验/CTRI/2024/09/073729
CTRI/2024/09/073729尚未招募不适用

A retrospective study of pharmacological non-compliance in patients of schizophrenia with respect to quality of life

DATTA MEGHE INSTITUTE OF HIGHER EDUCATION AND RESEARCH1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2024年10月10日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
90
试验地点
1
主要终点
A comprehensive outcome of poor compliance to Treatment of Schizophrenia on the outcome of disease.

研究概览

简要总结

Schizophrenia is a mental disorder that disruptsthought processes, perceptions, emotional responsiveness, and socialinteractions. Although the course of schizophrenia differs from person toperson, it is usually chronic and can be severe and disabling, resulting insignificant impairments in quality of life. As treatment As approaches evolved, more emphasis was placed on re-integrating patients intotheir psychosocial environments rather than simply monitoring psychoticsymptoms. With the increasing availability of a wide range of drugs to treatmental illnesses, psychotropic medications are now an essential component inthe treatment of patients with severe mental disorders. In For patients with schizophrenia, quality of life is an important aspect ofrecovery. Quality of life (QoL) is a term that refers to the wellbeing of apopulation or an individual in terms of both positive and negative aspects oftheir existence at a particular time. Personal health (physical,mental and spiritual), relationships, education status, work environment,social status, wealth, a sense of security and safety, freedom, and autonomy indecision-making, social-belonging, and their physical surroundings are examplesof common aspects of QoL.According to Boyer et al., one of the most important variables indetermining the recurrence of schizophrenia is QoL. The better the patient’s quality of life, the less likely they are to relapse within two years.Thedevelopment of second-generation antipsychotics raised expectations that thesemedications would improve quality of life more than traditional antipsychotics. Nearly one-third of people who suffer major psychiatric disorders globally endup with a long-term disability and dependency. However, very fewIndian studies have compared the change in quality-of-life following treatmentwith typical and atypical antipsychotics.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • INCLUSION CRITERIA: Patients who are clinically diagnosed to have Schizophrenia using the International Classification of Diseases 11th revision (ICD-11) research criteria Patients within the age group of 18 to 65 years.
  • The patient should be able to give written, informed consent.
  • Patient should be non-compliant at least for a period of 2 months.
  • Patients should be compliant at least for a period of a year.

排除标准

  • Subjects are not willing to give written informed consent.
  • Patients who are acutely ill or are not able to cooperate with the study Patients who have a history of developmental delay or any other major organic brain pathology.
  • Patient who had history of head injury.
  • Patients who have been non- compliant for less than 2 months.

结局指标

主要结局

A comprehensive outcome of poor compliance to Treatment of Schizophrenia on the outcome of disease.

时间窗: Assessments will be done at 6 months

次要结局

未报告次要终点

研究者

发起方
DATTA MEGHE INSTITUTE OF HIGHER EDUCATION AND RESEARCH
申办方类型
Research institution and hospital

研究点 (1)

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