Effect of intravenous lignocaine on postoperative opioid consumption and recovery after posterior spine fusion surgeries - A randomized controlled trial.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Enrollment
- 72
- Locations
- 1
- Primary Endpoint
- To determine the effect of intraoperative intravenous lignocaine infusion on postoperative opioid consumption during first 24 hrs after posterior spine fusion surgeries under general anaesthesia in 72 participants.
Study Overview
Brief Summary
I am doing this study to evaluate the effect of a drug (intravenous lignocaine) on postoperative opioid consumption (pain) and recovery after posterior spine fusion surgery. By being part of this study the patient may have decreased postoperative pain after the surgery and a better postoperative recovery.
Study Design
- Study Type
- Interventional
- Allocation
- Computer generated randomization
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Age 18-60 years of either sex.
- •Patients belonging to American society of Anesthesiologist physical status1 and
- •Patients undergoing posterior spine fusion surgeries under General anaesthesia.
Exclusion Criteria
- •Patients with allergy to local anaesthetic.
- •Patients undergoing spinal revision surgery .
- •Patients with bradycardia (HR< 50 bpm) and any rhythm abnormalities
- •Patients with seizure disorders.
- •Patients with uncontrolled diabetes, hypertension, chronic kidney disease, active coronary artery disease and severe COPD and Asthma.
Outcomes
Primary Outcomes
To determine the effect of intraoperative intravenous lignocaine infusion on postoperative opioid consumption during first 24 hrs after posterior spine fusion surgeries under general anaesthesia in 72 participants.
Time Frame: 24 hrs
OUTCOME VARIABLES:
Time Frame: 24 hrs
VAS score in both the groups in first 24 hrs.
Time Frame: 24 hrs
Quality of recovery using QOR – 15 scale
Time Frame: 24 hrs
Postoperative opioid consumption
Time Frame: 24 hrs
Hemodynamic parameters (SBP, DBP & MAP)
Time Frame: 24 hrs
Intraoperative opioid consumption
Time Frame: 24 hrs
Secondary Outcomes
- 1.To compare the postoperative VAS score in first 24 hrs in both the groups .(2.To compare the hemodynamic parameters (SBP, DBP & MAP) during the intraoperative period in both the groups.)