Effect of intravenous lignocaine on postoperative opioid consumption and recovery after posterior spine fusion surgeries - A randomized controlled trial.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- To determine the effect of intraoperative intravenous lignocaine infusion on postoperative opioid consumption during first 24 hrs after posterior spine fusion surgeries under general anaesthesia in 72 participants.
研究概览
简要总结
I am doing this study to evaluate the effect of a drug (intravenous lignocaine) on postoperative opioid consumption (pain) and recovery after posterior spine fusion surgery. By being part of this study the patient may have decreased postoperative pain after the surgery and a better postoperative recovery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Age 18-60 years of either sex.
- •Patients belonging to American society of Anesthesiologist physical status1 and
- •Patients undergoing posterior spine fusion surgeries under General anaesthesia.
排除标准
- •Patients with allergy to local anaesthetic.
- •Patients undergoing spinal revision surgery .
- •Patients with bradycardia (HR< 50 bpm) and any rhythm abnormalities
- •Patients with seizure disorders.
- •Patients with uncontrolled diabetes, hypertension, chronic kidney disease, active coronary artery disease and severe COPD and Asthma.
结局指标
主要结局
To determine the effect of intraoperative intravenous lignocaine infusion on postoperative opioid consumption during first 24 hrs after posterior spine fusion surgeries under general anaesthesia in 72 participants.
时间窗: 24 hrs
OUTCOME VARIABLES:
时间窗: 24 hrs
VAS score in both the groups in first 24 hrs.
时间窗: 24 hrs
Quality of recovery using QOR – 15 scale
时间窗: 24 hrs
Postoperative opioid consumption
时间窗: 24 hrs
Hemodynamic parameters (SBP, DBP & MAP)
时间窗: 24 hrs
Intraoperative opioid consumption
时间窗: 24 hrs
次要结局
- 1.To compare the postoperative VAS score in first 24 hrs in both the groups .(2.To compare the hemodynamic parameters (SBP, DBP & MAP) during the intraoperative period in both the groups.)