To compare efficacy of levobupivacaine alone or alongwith lignocaine with adrenaline in ultrasound guided supraclavicular block for upper limb surgeries in reducing pain and quality of recovery afterwards.
- Conditions
- Unspecified fracture of forearm, (2) ICD-10 Condition: S520||Fracture of upper end of ulna, (3) ICD-10 Condition: S521||Fracture of upper end of radius, (4) ICD-10 Condition: S522||Fracture of shaft of ulna, (5) ICD-10 Condition: S523||Fracture of shaft of radius, (6) ICD-10 Condition: S525||Fracture of lower end of radius, (7) ICD-10 Condition: S526||Fracture of lower end of ulna, (8) ICD-10 Condition: S424||Fracture of lower end of humerus,
- Registration Number
- CTRI/2023/03/050744
- Lead Sponsor
- Government medical college
- Brief Summary
Current study is to research the effect of lignocaine as an adjuvant to levobupivacaine for advancement of scientific knowledge.
The aim of this study is to compare the perioperative efficacy and recovery quality of ultrasound guided supraclavicular block administered using levobupivacaine with or without lignocaine with adrenaline for conduct of upper limb surgeries. Patients will be randomly divided into two groups (LLB and LL) with 40 patients in each group. The nerve bundle will be identified and infiltrated with the local anesthetic after negative aspiration for blood and no intraneural spread as visualized with ultrasound. Group LB will receive 28 mL of 0.5% levobupivacaine and 2 mL of normal saline while the Group LLB will receive 14 ml of 0.5% levobupivacaine,14 ml of lignocaine with adrenaline and 2 ml of normal saline making a total 30 ml of anestheticsolution. Patients will be observed for onset and duration of spinal and motor blockade in both the groups. The hemodynamic changes and side effects if any, would also be noted and compared amongst two groups. Postoperative analgesia requirement with rescue analgesia using injection Paracetamol 1gm intravenously.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 80
ASA I , II, III.
Infection at local sites, hypersensitivity to Local Anaesthetic drugs, per existing neuropathy, bleeding disorders,pregnancy, any hepatic , renal,neurological,psychiatric or neuromuscular diseases.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 2 to measure total analgesic requirement 1) time at which first rescue analgesia given will be recorded. | 2) total analgesia required in 24 hours. 1 To measure first rescue analgesia 1) time at which first rescue analgesia given will be recorded. | 2) total analgesia required in 24 hours.
- Secondary Outcome Measures
Name Time Method 1)to compare QoR score in both groups. 2) to blockade characteristics
Trial Locations
- Locations (1)
Bhagat phool Singh Government Medical College
🇮🇳Sonipat, HARYANA, India
Bhagat phool Singh Government Medical College🇮🇳Sonipat, HARYANA, IndiaDr JYOTIPrincipal investigator9711764546drjyotilh@gmail.com