Spinal Anaesthesia for Knee Arthroscopy: Does Lignocaine Shorten the Effect of Bupivacaine?

Frederikssunds Hospital, Denmark2 sites in 1 country60 target enrollmentNovember 2009

ConditionsSpinal Anesthesia

Interventionsbupivacaine Lidocaine

DrugsLidocaine bupivacaine

Overview

Phase: Phase 4
Intervention: bupivacaine
Conditions: Spinal Anesthesia
Sponsor: Frederikssunds Hospital, Denmark
Enrollment: 60
Locations: 2
Primary Endpoint: Duration of spinal blockade
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of the study is to investigate if a small amount of lignocaine added to bupivacaine for spinal anesthesia to patients planned for arthroscopic knee surgery, can shorten the duration of the sensoric and the motoric blockade.

Registry

clinicaltrials.gov

Start Date

November 2009

End Date

December 2010

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Frederikssunds Hospital, Denmark

Responsible Party

Principal Investigator

Jon Jacobsen

Chief consultant

Frederikssunds Hospital, Denmark

Eligibility Criteria

Inclusion Criteria

•The patient want spinal anaesthesia
•No contradictions against spinal anaesthesia
•Healthy people (ASA-score 1 or 2)
•Body mass index \< 35 and between 155 and 190 cm

Exclusion Criteria

•Known allergic reactions to planned drugs
•Neurologic disturbances

Arms & Interventions

Bupivacaine

Bupivacaine as used routinely

Intervention: bupivacaine

Lidocaine added to bupivacaine

lidocaine is added to bupivacaine

Intervention: Lidocaine

Lidocaine added to bupivacaine

lidocaine is added to bupivacaine

Intervention: bupivacaine

Outcomes

Primary Outcomes

Duration of spinal blockade

Time Frame: Repeating monitoring every 15 minutes after applying the blockade, up to 360 minutes.

Secondary Outcomes

Time to fulfillment of discharge criteria from the hospital.(Evaluated every 15 minutes after the operation up to 360 minutes. On average 200 to 300 minutes.)