Spinal Anaesthesia for Knee Arthroscopy: Does Lignocaine Shorten the Effect of Bupivacaine

Phase 4

Completed

• Conditions: Spinal Anesthesia
• Interventions: Drug: Lidocaine; Drug: bupivacaine

• Registration Number: NCT01245868
• Lead Sponsor: Frederikssunds Hospital, Denmark

Brief Summary

The purpose of the study is to investigate if a small amount of lignocaine added to bupivacaine for spinal anesthesia to patients planned for arthroscopic knee surgery, can shorten the duration of the sensoric and the motoric blockade.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-11
• Study First Submitted: 2010-06-14
• Study First Submitted QC: 2010-11-22
• Study First Posted: 2010-11-23
• Primary Completion: 2010-12
• Study Completion: 2010-12
• Status Verified: 2015-05
• Last Update Submitted: 2015-05-07
• Last Update Posted: 2015-05-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• The patient want spinal anaesthesia
• No contradictions against spinal anaesthesia
• Healthy people (ASA-score 1 or 2)
• Body mass index < 35 and between 155 and 190 cm

Exclusion Criteria

• Known allergic reactions to planned drugs
• Neurologic disturbances
• Diabetes

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lidocaine added to bupivacaine	bupivacaine	lidocaine is added to bupivacaine
Bupivacaine	bupivacaine	Bupivacaine as used routinely
Lidocaine added to bupivacaine	Lidocaine	lidocaine is added to bupivacaine

Primary Outcome Measures

Name	Time	Method
Duration of spinal blockade	Repeating monitoring every 15 minutes after applying the blockade, up to 360 minutes.

Secondary Outcome Measures

Name	Time	Method
Time to fulfillment of discharge criteria from the hospital.	Evaluated every 15 minutes after the operation up to 360 minutes. On average 200 to 300 minutes.

Trial Locations

Locations (2)

Dep. of anesthesiology, Hospital of Frederikssund; 🇩🇰 Frederikssund, Denmark

Jon Jacobsen; 🇩🇰 Frederikssund, Denmark