The use of intravenous lignocaine to reduce opioid consumption postoperatively and enhance recovery in posterior spine fusion surgeries

Not yet recruiting

• Conditions: Spondylosis,

• Registration Number: CTRI/2023/06/053512
• Lead Sponsor: Pondicherry Institute of Medical Sciences

Brief Summary

I am doing this study to evaluate the effect of a drug (intravenous lignocaine) on postoperative opioid consumption (pain) and recovery after  posterior spine fusion surgery. By being part of this study the patient may have decreased postoperative pain after the surgery and a better postoperative recovery.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-03-06
• Study Start: 2023-06-13

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

• Age 18-60 years of either sex.
• Patients belonging to American society of Anesthesiologist physical status1 and 2.
• Patients undergoing posterior spine fusion surgeries under General anaesthesia.

Exclusion Criteria

• Patients with allergy to local anaesthetic.
• Patients undergoing spinal revision surgery .
• Patients with bradycardia (HR< 50 bpm) and any rhythm abnormalities 4.
• Patients with seizure disorders.
• Patients with uncontrolled diabetes, hypertension, chronic kidney disease, active coronary artery disease and severe COPD and Asthma.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the effect of intraoperative intravenous lignocaine infusion on postoperative opioid consumption during first 24 hrs after posterior spine fusion surgeries under general anaesthesia in 72 participants.	24 hrs
OUTCOME VARIABLES:	24 hrs
VAS score in both the groups in first 24 hrs.	24 hrs
Quality of recovery using QOR – 15 scale	24 hrs
Postoperative opioid consumption	24 hrs
Hemodynamic parameters (SBP, DBP & MAP)	24 hrs
Intraoperative opioid consumption	24 hrs

Secondary Outcome Measures

Name	Time	Method
1.To compare the postoperative VAS score in first 24 hrs in both the groups .	2.To compare the hemodynamic parameters (SBP, DBP & MAP) during the intraoperative period in both the groups.

Trial Locations

Locations (1)

Pondicherry Institute of Medical Sciences; 🇮🇳 Pondicherry, PONDICHERRY, India

Pondicherry Institute of Medical Sciences

🇮🇳Pondicherry, PONDICHERRY, India

Abinaya G

Principal investigator

9597387124

abinayagnanavel29@gmail.com