The Effect of Anodal tDCS on Motor Learning in Multiple Sclerosis

Not Applicable

Completed

• Conditions: Anodal tDCS; Recruitment Curves
• Interventions: Device: Transcranial Direct Current Stimulation (tDCS) (Neuroconn DC-stimulator)

• Registration Number: NCT01740830
• Lead Sponsor: Hasselt University

Brief Summary

The current study investigates the effects of tDCS in patients with multiple sclerosis (MS). The investigators hypothesize that anodal tDCS will increase motor performance in patients with MS.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-06
• Primary Completion: 2012-10
• Study Completion: 2012-10
• Study First Submitted: 2012-11-26
• Study First Submitted QC: 2012-11-30
• Study First Posted: 2012-12-04
• Status Verified: 2013-06
• Last Update Submitted: 2013-06-01
• Last Update Posted: 2013-06-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

• at least 18 years old
• male and female

Exclusion Criteria

• relapse in the last 3 months
• when not suitable for tDCS (screening)
• if TMS measures can not be completed

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Anodal tDCS	Transcranial Direct Current Stimulation (tDCS) (Neuroconn DC-stimulator)	-
Sham tDCS	Transcranial Direct Current Stimulation (tDCS) (Neuroconn DC-stimulator)	-

Primary Outcome Measures

Name	Time	Method
Motor performance on a unimanual sequence learning task	Baseline, during training and POST (30 min after baseline) intervention	Patients were instructed to perform a unimanual sequence-learning task consisting of sequential finger presses. The following parameters were measured: Correct sequences/mean inter tap interval (ITI), percentage correct key presses/mean ITI, percentage correct sequences, percentage correct key presses, mean ITI, and mean correct sequences in the performance interval.