The Effect of tDCS on Motor Performance and Cortical Excitability

Not Applicable

Completed

• Conditions: Cortical Excitability; Motor Performance; tDCS
• Interventions: Device: transcranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)

• Registration Number: NCT01740843
• Lead Sponsor: Hasselt University

Brief Summary

In this study the effect of tDCS intensity on motor performance and corticospinal (CS) excitability is evaluated. The investigators expect that a positive relationship between current intensity and motor performance/CS excitability.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-08
• Study First Submitted: 2012-11-26
• Study First Submitted QC: 2012-11-30
• Study First Posted: 2012-12-04
• Primary Completion: 2013-04
• Study Completion: 2013-06
• Status Verified: 2014-02
• Last Update Submitted: 2014-02-24
• Last Update Posted: 2014-02-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Healthy subjects

Exclusion Criteria

• Contraindications for tDCS/TMS
• TMS measurements have to be possible

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Low intensity anodal tDCS	transcranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)	tDCS will be administered for 10 min at 1mA
High intensity anodal tDCS	transcranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)	tDCS will be administered for 10 min at 2.5mA
Sham tDCS	transcranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)	Sham will be administered for 10 min at 0 mA

Primary Outcome Measures

Name	Time	Method
Change in motor performance	Baseline and POST (30 min after baseline) intervention	motor performance is assessed using different reaction time paradigms (simple reaction time, choice reaction time). This is done at baseline and immediately after the intervention (30 min after baseline)
Change in cortical excitability	Baseline and POST (30 min after baseline) intervention	Cortical excitability is measured using trancranial magnetic stimulation (TMS) measuring muscle evoked potentials (MEPs) at baseline and POST (30 min after baseline).