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Intervention of Air Pollution and Acute Coronary Syndrome

Not Applicable
Conditions
Acute Coronary Syndrome
Interventions
Device: mask
Registration Number
NCT04126434
Lead Sponsor
Peking University
Brief Summary

To determine the effect of intervention of ambient air pollution on acute coronary syndrome patients.

Detailed Description

To investgate the effect of wearing facemasks to decreasing levels of exposure to ambient air on acute coronary syndrome patients.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
200
Inclusion Criteria
  1. Non-smoker of any type during past six months and living in a non-smoking household.
  2. A diagnosis of myocardial infarction or unstable angina 7-90 days prior to signed informed consent.
Exclusion Criteria
  1. Unstable CV disorders including uncompensated heart failure, refractory angina, uncontrolled arrhythmias, critical valvular heart disease and severe hypertension.
  2. A history of infection with human immunodeficiency virus.
  3. History of malignancy including leukemia and lymphoma AND/OR any severe, life-threatening disease AND/OR history of drug abuse within the last 2 years.
  4. Pregnancy or intent to get pregnant during the study period.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
no maskingmasknot wearing facemask
maskingmaskwearing facemask
Primary Outcome Measures
NameTimeMethod
vascular functionsix months

Systolic blood pressure and diastolic blood pressure measured by omron HBP-1300

autonomic nervous functionsix months

Twenty four-hour electrocardiograms and heart rate variability

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Peking University ,School of Public Health

🇨🇳

Beijing, Beijing, China

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