Development and Testing of a Patient-facing Educational Tool About Liver Cancer Prevention

Recruiting

• Conditions: Liver Cancer

• Registration Number: NCT07010315
• Lead Sponsor: M.D. Anderson Cancer Center

Brief Summary

To develop and test liver cancer prevention educational material.

Detailed Description

Primary Objectives:

* To ensure the text for the site is understood by participants, participant comprehension will be measured qualitatively through cognitive testing. Adjustments will be made to the content, messages, and layout iteratively until interviewer notes show no large discrepancies between participant understanding and the meaning of the text.

* To ensure the site is easy to use, usability will be measured qualitatively through usability testing. Adjustments will be made to the functionality of the patient-facing portions of the web-based tool iteratively until interviewer notes indicate that participants are able to input their risk factors and download the personal summary on their own.

Secondary Objectives:

* To describe whether the site is acceptable to users, acceptability will be measured (as part of usability testing) with the Ottawa Acceptability Measures.

* To describe participants' knowledge of liver cancer risk factors, knowledge will be measured (as part of usability testing) with Knowledge Questions developed for this study.

Study Timeline

• Status Verified: 2025-05
• Study Start: 2025-05-01
• Study First Submitted: 2025-05-09
• Study First Submitted QC: 2025-05-29
• Last Update Submitted: 2025-05-29
• Study First Posted: 2025-06-08
• Last Update Posted: 2025-06-08
• Primary Completion: 2026-04-30
• Study Completion: 2027-04-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• At least 18 years old
• Participants at the HOPE Clinic
• Able to speak and read either English or Spanish
• For usability testing: Able to use and navigate websites on own smart phone or study computer

Exclusion Criteria

• Has been diagnosed with liver cancer
• Cannot provide consent or otherwise participate in research activities (e.g. vision or hearing impairment)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Usability Testing	Up to 1.5 hours	Usability will be measured qualitatively using a Usability Interview Guide. Usability will also be measured using the System Usability Scale. Acceptability will be measured with the Ottawa Acceptability Measures. Knowledge will be measured pre- and post- session using knowledge questions developed by the investigators and refined during cognitive testing.
Cognitive Testing	Up to 1.5 hours	Participant comprehension will be measured qualitatively through cognitive testing. In cognitive testing interviews, participants are asked to "think aloud" as they review and react to new information. Participants will be presented with the storyboard (mock-up) versions of the content and asked to describe in their own words what the information means to them. Cognitive interviews may include questions about content such as length, clarity of the language, and helpfulness of the educational material. A trained research team member will ask probing questions throughout interviews as needed. Based on patient feedback, modifications will be made iteratively to the content to ensure the content is understood and interpreted as intended. There is no post-survey for cognitive testing.

Trial Locations

Locations (1)

MD Anderson Cancer Center; 🇺🇸 Houston, Texas, United States