To study to observe the lakshanas of Doshaja Pandu in patients suffering from sickle cell anaemia.

Not yet recruiting

Conditions: Sickle-cell/Hb-C disease. Ayurveda Condition: PANDUROGAH,

Registration Number: CTRI/2023/11/060293

Lead Sponsor: Dr Nidhi Kevalsingh Gaharwar

Brief Summary: Ayurveda is the most ancient system of medicine. In the classification the disease Pandu felt in the group of varna in which there is a significant change in the normal colour of the body. The detail description of Panduroga and its classification starts from ayurvedic Samhitas. According to ayurveda the word Pandu denotes pale yellowish white colour. It is a disease in which person becomes pallor due to deficiency of Rakta dhatu in the body. Most of the acharyas accepted the disease under five categories Vataj, Pittaj, Kaphaj, Sannipataj, Mrudbhakshanjanya.

The Panduta means pallor on the skin, which is the cardinal sign found in anaemia according to modern science. Anaemia is defined as a haemoglobin concentration in blood below the lower limit of the normal range for the age and sex of the individual. A condition, in which the blood does not have enough healthy red blood cells.

Anaemia results from a lack of red blood cells or dysfunctional red blood cells in the body this leads to reduced oxygen flow to the body organs. In general anaemia seen as genetically, nutritional or blood loss disorder. Sickle cell anaemia is the type of anaemia which is a genetic disorder. The most important and widely prevalent type of haemoglobinopathy is due to the presence of sickle haemoglobin (Hbs) in the red blood cells. The red cells with Hbs develop ’Sickling’ when they are exposed to low oxygen tension sickle syndromes have the highest frequency in black race.

Although sickle cell anaemia is a genetic disorder but if one can correlate sickle cell anaemia with Doshaj pandu lakshana, it will help in early diagnosis and nidanparivarjana can be advice. Also it will help to give a supportive treatment according to type of Doshaj pandu correlated with sickle cell anaemia, hence this topic will be selected.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

1 Known case of sickle cell anaemia patient on the basis of RBC morphology 2 Irrespective of sex caste socio-economical class and marital status.

Exclusion Criteria

1 Sickle cell anaemia patient having multiple organ failure and patients on ventilator 2 Any other genetic disorders any other type of anaemia like iron deficiency pernicious aplastic anaemia.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the Doshaj Pandu lakshanas in known case of sickle cell anaemia	One Time

Secondary Outcome Measures

Name	Time	Method
Not applicable	Not applicable

Trial Locations

Locations (1): Ayurved Rugnalay and Sterling Multispeciality Hospital
🇮🇳
Pune, MAHARASHTRA, India
Ayurved Rugnalay and Sterling Multispeciality Hospital
🇮🇳Pune, MAHARASHTRA, India
Dr Nidhi Kevalsingh Gaharwar
Principal investigator
8308715892
nidhigaharwar11@gmail.com