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The clinical study of the safety and efficacy of denosumab for glucocorticoid-induced osteoporosis

Not Applicable
Conditions
Glucocorticoid-induced osteoporosis
Registration Number
JPRN-UMIN000015180
Lead Sponsor
Osaka Medical College
Brief Summary

Denosumab significantly increased the mean BMD of the lumbar spine and bilateral hip (5.8%, and 1.3%, respectively).

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
56
Inclusion Criteria

Not provided

Exclusion Criteria

Patients with hypocalcemia

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The change of bone mineral density after 6 months, 12 months, 18 months,and 24 months
Secondary Outcome Measures
NameTimeMethod
The change of bone metabolism marker (BAP and TRACP-5b) after 3 months, 6 months, 12 months, 18 months,and 24 months
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