The Effect of High-Dose Vitamin D Supplementation on Hand Grip Strength Recovery in Eldery patient with Distal Radius Fracture : A Double-blinded Randomized Controlled Trial
- Conditions
- Distal radius fractureDistal radius fractureHypovitaminosis DElderDistal radius fixationVitamin D supplementation
- Registration Number
- TCTR20240720001
- Lead Sponsor
- Siriraj hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 106
1. Patients older than 60 years.
2. Have a distal radius fracture from a low-energy trauma and received surgical treatment using ORIF (Open Reduction and Internal Fixation) with plate and screws within 21 days post-injury.
1. History of receiving vitamin D within the past 6 months
2. Inflammatory joint diseases such as RA, SLE, or Gout
3. Abnormalities in bone metabolism, such as CKD beyond stage IV
4. Diagnosed with neuromuscular or neurosensory conditions affecting wrist function
5. History of using steroids within the past 12 months
6. History of injury or fracture or surgery in both wrists
7. Hand disease from both congenital and acquired in both wrists
8. Cognitive impairment
9. History of severe allergic reactions to vitamin D supplements
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hand grip strength recovery at 6 months after surgery Jamar dynamometer
- Secondary Outcome Measures
Name Time Method Functional score 1 week, 6 week, 3 months, 6 months, 1 year Thai version of Patient-Rated Wrist Evaluation,Appendicular skeletal mass index (ASMI) 1 week, 6 week, 3 months, 6 months, 1 year dual-frequency bioelectrical impedance analysis,Vitamin D level 6 months electrochemiluminescence (ECL) binding assay,Radiographic alignment 1 week, 6 week, 3 months, 6 months, 1 year Intelli-Space PACS Enterprise (Philips)