comparative study of three ovulation trigger methods in IVF/ICSI in poor response
Phase 3
- Conditions
- infertility.Female infertility
- Registration Number
- IRCT20110908007513N16
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 150
Inclusion Criteria
According to the Blogna (Bologna) criteria, people who meet the following two criteria are:1- Age over 40 years or risk factor to reduce ovarian reserve such as history of ovarian surgery, etc.2 - History of poor previous response to IVF (less than 3 oocytes in the previous cycle)Abnormal ovarian reserve test AFC (number of antral follicles) less than 5 to 7 or AMH (antimullerian hormone) less than 1/1
Exclusion Criteria
Patients who become infected with the coronavirus during the cycle, patients who do not respond well to the ovulation stimulation cycle and do not actually have a follicle to empty, patients who mistakenly take medication during the cycle.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of the mean number of oocytes obtained and the rate of positive pregnancy serum test, frequency of pregnancy sac viscosity on ultrasound, frequency of fetal heart rate on ultrasound, frequency of pregnancy continuity up to 12 weeks of pregnancy are used in the three study groups. Timepoint: The time of oocyte count after ovuum pickup and the time of positive pregnancy test 2 weeks after embryo transfer and the time of pregnancy sac evaluation week after embryo transfer and the time of implantation test 5 weeks after embryo transfer and the time of pregnancy test 12 weeks in 12 weeks of pregnancy. Method of measurement: Evaluation of oocyte count after ovum pickup under a microscope to evaluate pregnancy test with HCG beta titration blood test and examination of pregnancy and pregnancy bags at 12 weeks with ultrasound.
- Secondary Outcome Measures
Name Time Method othing. Timepoint: nothing. Method of measurement: nothing.