Feasibility study of a non-contrast MRI-scan for breast cancer screening using Velocity Selective Arterial Spin Labeling
Phase 2
Completed
- Conditions
- breast cancer1002765610006232
- Registration Number
- NL-OMON50007
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
female patients scheduled for an MR-breast scan
patients volunteer to participate and are capable and prepared to sign an
informed consent
patients of 18 years or older.
Exclusion Criteria
patients who would otherwise not an undergo MR-breast scan
patients who are not able or willing to comply with breathing instructions
patients with contra-indications for Gadolinium-contrast agents
patients who underwent breast reduction.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>As the main study parameter VS-ASL and DCE-MRI scans will be compared on image<br /><br>quality based on visual scoring of three experienced radiologists. The readers<br /><br>will be blinded to original study interpretations. </p><br>
- Secondary Outcome Measures
Name Time Method <p>As secondary study parameter VS-ASL and DCE-MRI scans will be compared based on<br /><br>quantitative lesion characteristics, e.g. tumor size, relative signal<br /><br>enhancement of tumor, etc, as well as overall suspicion for cancer.<br /><br>In addition, VS-ASL and DCE-MRI outcome will be compared to biopsy results (if<br /><br>available).</p><br>