Development of a multiparametric MRI protocol for Evaluation of morphology, ventilation and perfusion of the lung without contrast media.

• Conditions: J00-J99; lung diseasecystic fibrosis; Diseases of the respiratory system

• Registration Number: DRKS00020802
• Lead Sponsor: niversitätsklinikum Ulm

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-23
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 350

Inclusion Criteria

Probands:
At least 18 years old.
no known lung desease

Patients:
At least 6 years old.
Known lung desease

Exclusion Criteria

• General exclusion criteria for MRI scan (pacemaker, insulin pump, valvular transplants, other metallic foreign matter in the body, etc.)
• pregnancy
• Concerning contrast media: profound renal failure (GFR< 30 ml/min), age < 18 years
• according to the doctor in charge all patients which are unlikely to meet the requirements of the study.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Definition and Validation of a MRI-protocol, that's suitable for evaluating lung structure and ventilation. <br>Validation of the protocol to be suitable for clinical routine and long term surveillance. <br>

Secondary Outcome Measures

Name	Time	Method
Evaluation of the perfusion of the lung.