An investigation of the relationships between pain, aerobic exercise, physical activity, sleep and mood in people with Parkinson's disease.

Completed

• Conditions: Parkinson's disease; Pain; Neurological - Parkinson's disease

• Registration Number: ACTRN12616001143415
• Lead Sponsor: The University of Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-08-23
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

People with PD:
Aged 40 years or over, living in the community and are able to walk at least 200m with or without a walking aid.
No changes to their usual Parkinson's disease medications in the prior 2 weeks.

Healthy Control Group
Aged 40 years or over, living in the community

Exclusion Criteria

People with PD:
People with neurological impairments other than those due to Parkinson's disease.
People with substantial cognitive impairment (i.e. mini-mental state examination below 24)
People with pain due to a known radiculopathy (i.e. a compressed nerve of the spine) or another diagnosed chronic pain condition (e.g. fibromyalgia) that is likely to interfere with the evaluation of the person’s safety and of the study outcome.
People with uncontrolled cardiovascular, metabolic or renal disease.

Healthy control group
People with neurological impairments.
People with substantial cognitive impairment (i.e. mini-mental state examination below 24)
People who experience significant pain (i.e. pain of >3/10 intensity for at least 2 days per week in the prior 3 months)
People with pain due to a known radiculopathy (i.e. a compressed nerve of the spine) or another diagnosed chronic pain condition (e.g. fibromyalgia) that is likely to interfere with the evaluation of the person’s safety and of the study outcome.
People with uncontrolled cardiovascular, metabolic or renal disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pressure pain threshold measured with a pressure algometer.[Collected immediately before and after each bout of treadmill walking, at the assessment sessions. ];Pain will be assessed using the Brief Pain Inventory, which assesses pain severity and the impact of pain on daily activities in the past week. This will be collected for people with PD who experience pain.[Participants will complete this once – they will be provided with it at the first assessment session and will return it at the second session. ]