RESISTANCE VERSUS AEROBIC EXERCISES ON Breast Cancer Patients

Not Applicable

• Conditions: Breast Cancer

• Registration Number: NCT04656457
• Lead Sponsor: Cairo University

Brief Summary

The purpose of the study is to evaluate which is more effective resistance or aerobic exercises on cancer related fatigue and immunity in breast cancer patients undergoing adjuvant chemotherapy.

Detailed Description

The problem of cancer related fatigue and decreased immunity, as a result of treatment with adjuvant chemotherapy in breast cancer patients is not well known.

Fatigue and decreased immunity have a negative impact on work, social relationships, mood, and daily activities and cause significant impairment in overall quality of life, Furthermore the need of this study is developed from the lack of information in the published studies about the effect of the treatment with chemotherapy among breast cancer patients on inducing fatigue and decreasing immunity and the effect of resistance and aerobic exercises on improving these changes.

Study Timeline

• Study First Submitted: 2020-11-23
• Study First Submitted QC: 2020-11-30
• Status Verified: 2020-12
• Study First Posted: 2020-12-07
• Study Start: 2020-12-12
• Last Update Submitted: 2021-01-26
• Last Update Posted: 2021-01-28
• Primary Completion: 2021-03-01
• Study Completion: 2021-04-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

The subject selection will be according to the following criteria:

1. Age range from 30-60 years.
2. Females post mastectomy only will participate in the study.
3. All patients undergoing adjuvant chemotherapy and have cancer related fatigue and decreased immunity.
4. All patients enrolled to the study will have their informed consent.

Exclusion Criteria

• The potential participants will be excluded if they meet one of the following criteria:

  1. Age more than 60 years or less than 30 years.
  2. Another concurrent malignant disease.
  3. Subjects suffering from any condition for which resistance or aerobic exercises contraindicated as metastasis, sever osteoporosis and cardiac diseases.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Hemoglobin level test for fatigue assessment	he evaluation will be conducted three months later	Hemoglobin levels are measured by a blood test. Hemoglobin, or Hb, is usually expressed in grams per deciliter (g/dL) of blood. A low level of hemoglobin in the blood relates directly to a low level of oxygen
Fatigue assessment scale	The evaluation will be conducted three months later	The Fatigue Assessment Scale (FAS) is quick and easy to complete for patients, and not time consuming. It is also helpful for physicians and other health care workers in the follow-up of their patients. The FAS has proven to be a valid questionnaire to assess fatigue in cancer patients, but also in many other patients with chronic diseases
White blood cells count test for immunity assessment	he evaluation will be conducted three months later	White blood cells (also called leukocytes and abbreviated as WBCs) are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. Leukocytes are found throughout the body, including the blood and lymphatic system

Trial Locations

Locations (1)

Medical research institute; 🇪🇬 Alexandria, Egypt