The effect of isotretinoin on acne scars in patients treated with a fractional CO2 laser

Phase 2

Completed

• Conditions: Patients with acne scars; Acne scars

• Registration Number: TCTR20221010002
• Lead Sponsor: Division of Dermatology, Department of internal medicine

Brief Summary

Edema - higher occurrence in non-isotretinoin group at every session. no difference in severity. Crusting- in the first session non-isotretinoin has significantly higher proportion of severe crusting (p 0.006) however no statistical significance was found after 2nd and 3rd session Erythema - no statistical significance of severity proportion was found between two groups Post-inflammatory hyperpigmentation no significant in severity proportion was observed throughout the study.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-10
• Study Completion: 2024-02-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Healthy patients with acne scars

Exclusion Criteria

Receiving acne scar therapy or laser within 6 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Skin Depression 0,1, 3, 6 months Antera 3D

Secondary Outcome Measures

Name	Time	Method
Skin texture 0,1,3,6 months Antera 3D,Brown spots 0,1,3,6 months Visia,Side effects 0,1,3,6 months 4-point scale,Patient's satisfaction 1 3 6 months Satisfaction score (VAS)