Prevalence and Genetic Alternation of Autoimmune Polyglandular Syndrome Type II in Taiwan
Recruiting
- Conditions
- Autoimmune Polyendocrine Syndrome Type II
- Interventions
- Other: no intervention
- Registration Number
- NCT05578105
- Lead Sponsor
- National Taiwan University Hospital
- Brief Summary
Autoimmune polyendocrine syndrome (APS) is an autoimmune disease involving at least two endocrine organ. It is classified into type I and type II diseases. Among them, APS type II is more common. It is diagnosed when two of the three following diseases are diagnosed in the same patient, including type 1 diabetes mellitus, autoimmune thyroid disease, and primary adrenal insufficiency. In this study, we will observe the epidemiology, clinical characteristics, and genetic variants of APS II in Taiwan.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 650
Inclusion Criteria
- Patients visited NTUH during 2006-2021, and had at least two of the three diseases: type 1 DM, primary adrenal insufficiency, and autoimmune thyroid disease.
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Exclusion Criteria
- Patients aged less than 20 years old
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Autoimmune polyendocrine syndrome type II no intervention patients with autoimmune polyendocrine syndrome type II
- Primary Outcome Measures
Name Time Method Rates of endocrine organs involved 2022/1/1 ~ 2026/12/31 We will observe the rate of each endocrine organ involved, including adrenal gland, thyroid, and pancreas
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
National Taiwan University Hospital
🇨🇳Taipei, Taiwan