Acute Efficacy of Point-by-point Radiofrequency Ablation for Pulmonary Vein Isolation in Patients With Atrial Fibrillation: a Randomized Comparison of Continuous Versus Discontinuous Design of Encircling Lesions
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Combined unsuccessful PVI or PV reconnection
研究概览
简要总结
Acute efficacy of point-by-point radiofrequency ablation for pulmonary vein isolation in patients with atrial fibrillation are comparable independantly of the ablation strategy (continous versus discontinuous ablation) under the same condition of power delivery.
详细描述
The number of pulmonary vein isolation (PVI) therapy for atrial fibrillation (AF) is increasing. Durable PVI is cornerstone for long-term freedom of AF. In one previous study continuous ablation was suggested to be more efficient in durable PVI. However, this hypothesis has not been proven in randomized fashion.
The current study is to confirm whether continuous versus discontinuous design of encircling lesions are comparable under the same conditions of power delivery.
The study design is a two-centre prospective randomized trial to compare the acute efficacy by using the above described approaches.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing pulmonary vein isolation with radiofrequency catheter ablation for paroxysmal atrial fibrillation treatment.
排除标准
- 未提供
研究组 & 干预措施
Discontinuous ablation
perform discontinuous ablation of ipsilateral pulmunary veins.
干预措施: catheter ablation (Procedure)
Continuous ablation
perform continuous ablation of ipsilateral pulmunary veins.
干预措施: catheter ablation (Procedure)
结局指标
主要结局
Combined unsuccessful PVI or PV reconnection
时间窗: 30 min after ablation
Combined unsuccessfuk PVI after completeing the primary lesion set or PV reconnection during the waiting time
次要结局
- Early pulmunary veins reconnection(10 min.)
研究者
Bashar Aldhoon
Dr. Bashar Aldhoon, PhD
Institute for Clinical and Experimental Medicine