Comparing two methods of oral Azithromycin and cryotherapy in cutaneous leishmaniasis treatment in childre
Phase 2
- Conditions
- Cutaneous Leishmaniasis.Cutaneous leishmaniasis
- Registration Number
- IRCT138903023862N3
- Lead Sponsor
- Research Council of Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 66
Inclusion Criteria
presence of cutaneous leishmaniasis with less than 6 months of clinical course that their disease have been approved by direct smear and stained with giemsa method or skin biopsy, age<14, a 3-month treatment free interval from the last treatment course. Exclusion criteria: pregnancy, lactating, receiving simultaneously any therapy that has antileishmaniasis effect during 2 months ago, history of significance renal, pulmonary and cardiovascular disease, sensitive to azithromycin.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete healing. Timepoint: For the first intervention, at the end of each month until 4 months and for second intervention at the end of 8th week and during follow up of patients in both studied group after 3 months of beginning of the study. Method of measurement: Measuring the size of induration and ulcer.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: At each follow up visit. Method of measurement: physical exam.