Comparison of the effectiveness of azithromycin capsules and zinc elemental capsules with azithromycin capsules alone in the treatment of acne vulgaris

Phase 2

Recruiting

Conditions: Acne vulgaris
mild to moderate acne vulgaris.
L70.0

Registration Number: IRCT20091012002581N12

Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Patients with mild to moderate acne aged 11-30 years
Patients who have more than 20 inflammatory lesions (papules and pustules) on one side of the face and no more than three nodules or cysts on the same side of the face.
Not having other skin diseases involving the face
Having patient satisfaction
Not having other systemic diseases aggravating acne, such as Cushing's syndrome, PCO, adrenal hyperplasia, acquired and innate immune deficiency, steroid acne and acneiform rashes, etc.
Patients who have not used oral or topical anti-acne drugs in the last month, including natural and UV light and herbal and traditional acne treatments.

Exclusion Criteria

Patients who use topical or systemic steroids.
Patients who use anti-androgen combinations.
Patients who have used oral or topical anti-acne drugs even including natural light and UV in the last month.
The presence of other facial skin dermatoses and other systemic diseases that aggravate acne, such as Cushing's syndrome, PCO, adrenal hyperplasia, acquired and innate immune deficiency, steroid acne and acneiform rashes, etc.
Patient dissatisfaction
The presence of more than three nodules or cysts on one side of the face
Patients with excoriate acne
Age below 11 years and above 30 years
Having an inflammatory disease on the face other than acne, such as contact, allergic or seborrheic dermatitis, etc.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity. Timepoint: Every 30 days. Method of measurement: History and clinical examination.

Secondary Outcome Measures

Name	Time	Method
Patient satisfaction. Timepoint: every 30 days. Method of measurement: Questionnare.;Total acne lesions. Timepoint: Every 30 days. Method of measurement: clinical examination.;Index of acne severity. Timepoint: every 30 days. Method of measurement: clinical examination.