A clinical trial to study the effect of doxycycline in patients of chronic obstructive pulmonary disease with stable symptoms
- Conditions
- Health Condition 1: null- Chronic obstructive pulmonary disease
- Registration Number
- CTRI/2011/091/000042
- Lead Sponsor
- Govt Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 72
1.Age > 40 years
2.Smoking history >10 packs years
3.Patients classified as GOLD criteria II and III
4.Ability to perform Pulmonary function tests
1.Patient with acute exacerbation (Anthonisen et al) / critically ill patients
2.Patient with moderate/severe exacerbation in last 4 weeks as defined by severity scale proposed by Cazzola et al.
3.Patient with active respiratory disease other than COPD (tuberculosis, lung malignancies, Bronchiectasis, pneumonia, bronchial asthma)
4.Patient with acute systemic/local infection
5.Patient with cardiac disease (CCF, Recent myocardial infarction, Cardiac arrhythmias)
6.Patient with gastrointestinal disorders (Gastro-esophageal reflux disorder, peptic ulcer, Undiagnosed abdominal pain)
7.Patient with renal or hepatic impairment
8.Patient with h/o hypersensitivity to tetracyclines
9.Patient receiving oral corticosteroids
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method