Plasma RBP Levels in Patients With Idiopathic Hypogonadotrophic Hypogonadism
- Conditions
- Idiopathic Hypogonadotropic Hypogonadism
- Interventions
- Drug: Sustanon 250 mg ampule (Testosterone esters)
- Registration Number
- NCT01758094
- Lead Sponsor
- Gulhane School of Medicine
- Brief Summary
The aim of the present study was to demonstrate the RBP4 levels, association of RBP4 with insulin resistance and influence of testosterone treatment on this cytokine in patients with idiopathic hypogonadotropic hypogonadism.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 25
decreased serum testosterone concentration below the normal range (serum T < 300ng/dL), FSH and LH levels within or below the normal range, absence of a pituitary or hypothalamic mass lesions on MRI, presence of gonadotropin response to repetitive doses of GnRH, normal smell test and normal karyotypes
previous androgen treatment, history of smoking, presence of bilateral anorchia, intellectual deficiency, diabetes mellitus, arterial hypertension or dyslipoproteinemia, medication of any kind and drug abuse. Because of possible confounding effects, patients with other hormone deficiencies were excluded.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Hypogonadotropic hypogonadism patients Sustanon 250 mg ampule (Testosterone esters) Treatment naive 25 patients with idiopathic hypogonadotrophic hypogonadism
- Primary Outcome Measures
Name Time Method Retinol binding protein 4, hs-CRP levels in patients with idiopathic hypogonadotrophic hypogonadism 2008-2012
- Secondary Outcome Measures
Name Time Method Effect of testosterone treatment on retinol binding globulin 4 and hs-CRP levels in patients with hypogodotrophic hypogonadism 2008-2012
Trial Locations
- Locations (1)
Gulhane School of Medicine Dep. of Endocrinology and Metabolism
🇹🇷Ankara, Turkey