Influence of Emotions on Decision-making in Parkinson's Disease
- Conditions
- Parkinson Disease
- Interventions
- Other: cognitive examinationOther: viewing of videoOther: Iowa Gambling Task
- Registration Number
- NCT03342339
- Brief Summary
Parkinson's disease mainly affects the dopaminergic neurons of the Substancia nigra, which project on the striatum. Neuronal death within this structure leads to a decrease in dopamine levels. Dopamine is a neurotransmitter essential to the proper functioning of the basal ganglia highly involved in the control of voluntary and involuntary movements.
It also leads to cognitive and behavioral changes. Among these changes, the investigators will mainly remember the idea of the emergence of difficulties to make the right decisions, for example at the financial, medical .... This disruption would be the result of executive dysfunction. By definition, executive functions allow us to evaluate, plan and organize our actions to achieve a goal.
- Detailed Description
Some research shows that positive emotional states are associated with greater self-confidence, greater optimism, and better regulation of our decision-making. The goal is to test whether positive emotional induction could improve decision-making in Parkinson's disease.
Listening to music would decrease anxiety levels and increase self-esteem levels. Who says Parkinson says dopamine deficiency and so the investigators can think that the investigators can help patients by inducing a positive emotion through musical stimulation.
All participants will be subject to emotional induction. They will be divided into two different conditions: either they will be induced in a positive state, or they will be maintained in a neutral state. For this, video clips (positive or neutral) containing music will be presented. Immediately after the presentation of the video, participants will have to perform the Iowa Gambling Task test. This is a sequential task to evaluate decision-making capabilities.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 44
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description witnesses cognitive examination 1. cognitive examination : mini mental test of Parkinson, Hospital Anxiety and Depression Scale, 5 words by Dubois, fast test frontal assessment, Trail Making Test 2. viewing of video : scale of differential emotions and Positive and Negative Affect Scale 3. Test of Iowa Gambling Task patients with Parkinson's disease viewing of video 1. cognitive examination : mini mental test of Parkinson, Hospital Anxiety and Depression Scale, 5 words by Dubois, fast test frontal assessment, Trail Making Test 2. viewing of video : scale of differential emotions and Positive and Negative Affect Scale 3. Test of Iowa Gambling Task patients with Parkinson's disease cognitive examination 1. cognitive examination : mini mental test of Parkinson, Hospital Anxiety and Depression Scale, 5 words by Dubois, fast test frontal assessment, Trail Making Test 2. viewing of video : scale of differential emotions and Positive and Negative Affect Scale 3. Test of Iowa Gambling Task patients with Parkinson's disease Iowa Gambling Task 1. cognitive examination : mini mental test of Parkinson, Hospital Anxiety and Depression Scale, 5 words by Dubois, fast test frontal assessment, Trail Making Test 2. viewing of video : scale of differential emotions and Positive and Negative Affect Scale 3. Test of Iowa Gambling Task witnesses viewing of video 1. cognitive examination : mini mental test of Parkinson, Hospital Anxiety and Depression Scale, 5 words by Dubois, fast test frontal assessment, Trail Making Test 2. viewing of video : scale of differential emotions and Positive and Negative Affect Scale 3. Test of Iowa Gambling Task witnesses Iowa Gambling Task 1. cognitive examination : mini mental test of Parkinson, Hospital Anxiety and Depression Scale, 5 words by Dubois, fast test frontal assessment, Trail Making Test 2. viewing of video : scale of differential emotions and Positive and Negative Affect Scale 3. Test of Iowa Gambling Task
- Primary Outcome Measures
Name Time Method net score of Iowa Gambling Task Test day 1 calculated by adding the number of cards taken in the right pile and subtracting it from the number of cards chosen in the wrong pile
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
CHU de Saint Etienne
🇫🇷Saint-Étienne, France
CHU de Grenoble Alpes
🇫🇷Grenoble, France