Skip to main content
Clinical Trials/NCT03342339
NCT03342339
Completed
Not Applicable

Influence of Emotions on Decision-making in Parkinson's Disease

Centre Hospitalier Universitaire de Saint Etienne2 sites in 1 country44 target enrollmentFebruary 8, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Parkinson Disease
Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Enrollment
44
Locations
2
Primary Endpoint
net score of Iowa Gambling Task Test
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

Parkinson's disease mainly affects the dopaminergic neurons of the Substancia nigra, which project on the striatum. Neuronal death within this structure leads to a decrease in dopamine levels. Dopamine is a neurotransmitter essential to the proper functioning of the basal ganglia highly involved in the control of voluntary and involuntary movements.

It also leads to cognitive and behavioral changes. Among these changes, the investigators will mainly remember the idea of the emergence of difficulties to make the right decisions, for example at the financial, medical .... This disruption would be the result of executive dysfunction. By definition, executive functions allow us to evaluate, plan and organize our actions to achieve a goal.

Detailed Description

Some research shows that positive emotional states are associated with greater self-confidence, greater optimism, and better regulation of our decision-making. The goal is to test whether positive emotional induction could improve decision-making in Parkinson's disease. Listening to music would decrease anxiety levels and increase self-esteem levels. Who says Parkinson says dopamine deficiency and so the investigators can think that the investigators can help patients by inducing a positive emotion through musical stimulation. All participants will be subject to emotional induction. They will be divided into two different conditions: either they will be induced in a positive state, or they will be maintained in a neutral state. For this, video clips (positive or neutral) containing music will be presented. Immediately after the presentation of the video, participants will have to perform the Iowa Gambling Task test. This is a sequential task to evaluate decision-making capabilities.

Registry
clinicaltrials.gov
Start Date
February 8, 2018
End Date
February 20, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

net score of Iowa Gambling Task Test

Time Frame: day 1

calculated by adding the number of cards taken in the right pile and subtracting it from the number of cards chosen in the wrong pile

Study Sites (2)

Loading locations...

Similar Trials