Effect of food matrix on bioavailability of cocoa polyphenols - Cocoa bioavailability

Academisch Medisch Centrum0 个研究点目标入组 12 人开始时间: 待定最近更新: 2024年5月13日

适应症

试验速览

暂无简介。

•Age 18-70 years
•Body Mass Index (BMI) 19-30 kg/m2
•Reported alcohol consumption < 28 alcohol units/week
•Willing to refrain from food and foodsupplements that contain polyphenols during the study
•Informed consent signed
•Prepared to consume test products for the duration of the study and comply with the background diet.
•Prepared to donate blood samples during the study, and prepared to fill out questionnaires.
•Urine parameters within normal reference range as judged by the research physician
•Clinical chemical parameters within the normal reference range as judged by research physician
•Accessible veins on both arms as determined by research physician

•Being an employee of the AMC
•A recorded history or current metabolic diseases, chronic gastrointestinal disorders, cardiovascular or renal disease
•Currently on a medically prescribed diet, or slimming diet
•Reported intense sporting activities > 10 hours/week
•Subjects who receive medical treatment
•Any surgery in the past 6 months
•Use of systemic antibiotics in the past 3 months
•Recent blood donation i.e. 1 month prior to the study and no planned blood donation during the study period
•Known intolerance or allergy to cocoa, soy or lactose
•Reported weight change ± 10% the past 6 months
•Participation in another biomedical study 3 months before the start or during the study
•The habit of smoking during the past year
•Consuming meat and/or fish less than twice a week
•Participation in night shift work

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